As they burned the body of Sinope, Callisto entered into a state of grief for the next 50 years and refused to speak or participate in any human activity. He was found often staring into the sky, mumbling to himself and weeping. One day, the Gods Shaitan and Thoth, sensing the potential in humanity that Caymus, the Aldar prophet, first did, and wishing to use them for their own purposes, appeared to Callisto and argued that Anake should suffer for his terrible deed. They conjured up vivid visions of beautiful Sinope, and Callisto became mad with grief. Screaming out his rage, he left Ceylon, unseen by his children and grandchildren and spent fourteen years in the wilderness, tracking down Anake. When he finally found them, he was more animal than human. He rushed into the forest dwelling that Anake, Lysithea, and their only two children, Rukal and Lakspura inhabited, and brutally killed Anake while he slept. As he slit Anake's throat with a piece of sharp obsidian, Anake's blood splattered Callisto's face. Callisto, feeling the blood of his son flowing down his face in smooth rivulets, went irreparably insane.

Running and screaming, tears streaming down his face as he pleaded with Sarapis to end his miserable life, he was grabbed by a pair of hands from above. Quickly they wrapped a rope around his neck, dropped him, and hung him. As Callisto's neck snapped, Rukal and Lakspura looked at each other with satisfaction, having avenged their father's death at the hands of their grandfather.